Nail Fungus Medical Studies

Bio-Oxidatives (Highly oxygenated chemicals) why they help fight Nail Fungus Infection

lab-technician-537x358Our nail fungus treatment is effective because we flood the area with oxygen; we use ozone to achieve this because it has an extra oxygen atom. We take highly anti-fungal oil (manuka oil) and infuse it with ozone which is also highly anti-fungal to make an Ozone Oil. Flooding the area with oxygen also increases nail growth significantly. No other toenail fungus treatment is designed to do this.

One of our most effective active ingredients we use is ozone, it is a bio-oxidive, it is made up of 3 oxygen atoms, we use this ingredient to flood the infected area with oxygen. Ozone has exceptional anti–microbial characteristics.

A study was undertaken recently by researchers at the Pasteur Polyclinic in Cuba. Using ozonized oil, the same substance we use as an active ingredient in our Toenail fungus treatment, it was used to treat patients suffering from epidermophitosis (a fungal infection) resistant to the standard treatments.

The group was comprised of 100 patients. 50 of them were treated with ozonized oil, applied topically 3 times a day. The other 50 were given conventional treatments, also applied 3 times a day. An amazing 96% of the patients treated with the ozonized oil were cured within 10 to 15 days. In the control group, only 20% were cured in 15 days.

Ozonized oil and its efficacy in epidermophitosis.
De las Cagigas T., Bastard V., Menéndez S.1, Gómez M.1 and Eng L.1.
Clinic of the family physician from Pasteur Polyclinic, Cuba.
National Center for Scientific Research, Cuba.

According to Frank Shallenberger, M.D

(1) Bio-oxidatives – (The saturated oxygen in our cream) works because –

  • 1. They stimulate the production of white blood cells, which are necessary to fight infection.
  • 2. Bio-oxidatives are anti-viral and anti-fungal.
  • 3. They increase oxygen and hemoglobin disassociation, thus increasing the delivery of oxygen from the blood to the cells. This is why nail growth is remarkably increased.
  • 4. They increase red blood cell membrane distensibility, thus enhancing their flexibility and effectiveness. Also why nail growth is remarkably increased.
  • 5. Bio-oxidatives increase tissue oxygenation, thus bringing about patient improvement. Again this increases nail growth.


H202: What it is and why it is in our nail fungus treatment cream

H2O2 (another bio-oxidative also in our cream) is involved in all of life’s vital processes, and must be present for the immune system to function properly. The cells in the body that fight infection (known as granulocytes) produce H2O2 as a first line of defense against invading organisms like parasites, viruses, bacteria and yeast. Some of the biological killing activity of H202 can be attributed to gamma interferon. Production of gamma interferon by human natural killer cells and monocytes, is stimulated by H202 (2).

H2O2 has long been used medically as a disinfectant, antiseptic and oxidizer, but has only recently been found to successfully treat a wide variety of human diseases with a minimum of harmful side effects

H2O2 appears to be involved in many intermediate biochemical pathways. Additionally, it appears to kill certain bacteria, parasites, yeast, protozoa, inhibit viruses, and oxidize immunocomplexes. T. Ramasarma (3)

If that wasn’t enough we added Manuka Oil

bees-on-manuka-honeyHow Manuka Oil Fights your Nail Fungus Infection

Manuka oil has shown effectiveness in laboratory tests against 39 separate micro-organisms(4) (Including – Trichophyton mentagrophytes and Trichophyton rubrum- responsible for Toenail Fungus, Nail Fungus & Tinea

The oil has been tested against 39 separate micro-organisms and has been found active against all of them. A list of some of these follows with the MIC (Minimum Inhibitory Concentration) for each. MIC of oil is the lowest concentration that will inhibit the growth of a specified micro-organism. Near the bottom is Trichophyton mentagrophytes and Trichophyton rubrum- responsible for Toenail fungus, Nail Fungus & Tinea


Gram Positive Bacteria MIC

Staphylococcus aureas 0.039
Staphylococcus aureas methacillin resistant 0.0195
Staphylococcus epidermidis 0.078
Streptococcus faecalis 0.039
Streptococcus agalactiae 0.039
Micrococcus luteus 0.0195
Sarcina lutea 0.078
Bacillus subtilis 0.156
Listeria monocytogenes 0.039

Gram Negative Bacteria %

Escherichia coli 2.5
Pseudomonas aeruginosa 997 2.5
Klebsiella pneumoniae 5
Proteus vulgaris 5
Vibrio furnissii 0.625
Pseudomonas aeruginosa 2584 >5
Pseudomonas fluorscens 5

Fungi %

Trichophyton mentagrophytes 0.078
Trichophyton rubrum <0.039
Microsporum canis <0.039
Aspergillus niger >1.25
Candida Albicans 0.625

1. Frank, “Intravenous Ozone Therapy in HIV-related Disease” Proceedings: Fourth International Bio-Oxidative Medicine Conference, April 1993.

2. Archibald FS and Duong MN: Superoxide Dismutase and Oxygen Toxicity Defenses in the Genus Neisseria. Infect Immun 1986; 51(2): 631-41

3. Mallams JT, Finney JW, and Balla GA: The Use of Hydrogen Peroxide As A Source of Oxygen in A Regional Intra-Arterial Infusion System. So M J 1962; 55: 230-232.

4. Cooke A, Cooke MD, Cawthron Institute, An investigation into the Antimicrobial Properties of Manuka and Kanuka Oil, February 1991


This website is not intended to overturn professional medical advice and treatment from your doctor. Visitors are encouraged to consult qualified health professionals regarding the treatment of fungal conditions. The site owner shall not be held liable or responsible for any misinterpretation of the information presented on this website or for any damage, or supposed injury caused, either directly or indirectly by our fungal treatment creams presented in this site. The information is not intended to diagnose, cure, or prevent any disease.

*Individual results may vary.